PRODUCT DESCRIPTION
 POWERFUL ANTIOXIDANTS from PHYTO-NUTRIENTS (Plant Sources)
Biovin™ is a trademark extract and one of the most remarkable nutrients in supplement history and one of the most expensive as well. Cancer and cardiovascular disease are the two major causes of death in North America. Besides genetic factors and age, diet is considered a key risk factor associated with these diseases. Recent studies indicate that populations consuming grapes and grape products have a lower incidence of cancer and coronary heart disease. Studies have shown that the following compounds, derived from grapes, play a role in enhancing the antioxidant capacity of blood and protecting proteins and LDL Cholesterol against oxidative damage. OPCs also known as proathocyanidins and procyanidins, are found in the see of grapes and are most prevalent in red wine. Biovin™ works primarily because the grape phenols are highly bioavailable and absorbable through the blood.
Resveratrol is one of the hottest research ingredients and is naturally reoccurring in Biovin™ — and this helps minimize incidents of heart disease because Resveratrol inhibits LDL oxidation and platelet aggregation. Biovin™ helps increase intracellular vitamin C levels. It also helps poor capillary elasticity and structure by inhibiting the harmful enzymes elatase and collagenase. Finally, it helps inhibit destruction of collagen by supporting collagen structures and helps decrease excessive clumping of platelets. Med Factors™ contains 300mg of Biovin™. It is a very expensive ingredient and many companies who use it use lesser potencies to cut cost. All research Cyvex Corporation did and all claims for Biovin™ were done with 300mg; therefore, any product making any claims subject to the above statements should use 300mg. Natural Biology is known for using research potencies in all their products. Green tea extract contain a high content of polyphenols which are a class of bioflavonoids — primarily for fighting free radicals. 97% polyphenol extract is the highest form of Green Tea Extracts. Green tea extract contains a potent antioxidant, EGCG, which is over 200 times more powerful than vitamin E in neutralizing the pro-oxidants and free radicals that attack lipids in the brain. This important ingredient, Epigallocatechin Gallate (EGCG), protects against digestive and respiratory infections, helps to block the cancer promoting actions of carcinogens, protects against high total and LDL cholesterol levels, and blocks the attachment of the bacteria associated with dental cavities to the teeth. Green tea extract helps with thermogenesis and aids in the metabolism of fat. Known for years as a powerful antioxidant, it may also be helpful in shedding fat. The most obvious benefit to dieters is that it works without increasing the heart rate most often found in diet aids. The increased heart rate leaves dieters jittery and eventually, most dieters stop using the supplement and gain weight back. Now through using green tea extract, dieters get the weight loss benefits without any of the jittery effects, especially in obese individuals with hypertension and other cardiovascular complications.
Broccophane™ is a all-natural plant product standardized to contain a minimum of 4000 ppm sulforaphane. Sulforaphane has been shown to trigger the body’s natural defense against cancer by inducing the activity of Phase II enzymes. These enzymes scavenge and neutralize free radicals in the body before they can damage DNA and increase the risk of cancer. Broccophane is natural, safe, and efficacious. It may prevent growth of some malignant tumors or slow the growth of some. It is a possible protection with a bacteriocidal substance against Helicobacter pylori, a bacteria known to cause gastric and peptic ulcers, which may lead to gastric cancer. Sulforaphane reinforces the body’s natural responses to oxidative stress, prolonging the protective effect for several days. The recommended medical dose is 100mg per day which is the amount in Med Factors. Sulforaphane is a natural phytochemical found in cruceiferous vegetables including broccoli — thus the name Broccophane. Lutein is an antioxidant that has benefits for eye, skin and cardiovascular health. Lutein is a colorful compound found in fruit, corn, egg yolks and leafy green vegetables, such as spinach. One Harvard study suggests that eating a diet rich in these foods may reduce your risk of developing AMD -. Another study of AMD patients indicates a link between lutein and an improvement or reversal of some symptoms. Age-related macular degeneration or AMD is the most common cause of vision loss in older Americans. It occurs when cells in the middle part of the retina, called the macula, begin to degrade. As a result, central vision deteriorates, while peripheral vision remains intact. There is no cure, and the blindness associated with AMD is considered permanent. But researchers are working to change that. One source of hope is a powerful antioxidant called lutein. Lycopene, a carotenoid found in tomato products, prevents oxidation of low density lipoprotein (LDL) cholesterol and reduces the risk of developing atherosclerosis and coronary heart disease according to recent studies. High LDL oxidation is associated with increased risk of atherosclerosis and coronary heart disease. Ongoing research suggests that lycopene can reduce the risk of prostate cancer and cancers of the lung, bladder, cervix and skin. Zinc is a mineral essential for formation of superoxide dismutase, one of the body's most important free radical scavengers and one that cannot be directly supplemented. Zinc promotes wound healing, immune function, taste sensitivity, protein synthesis, insulin production, and reproduction including organ development and sperm motility. OptiZinc™ is recognized as the best available form of zinc on the market today. NAC is an antioxidant and a precursor to glutathione, another antioxidant that assists in the liver's detoxification pathways. NAC is the acetylated form of L-cysteine. It is a more stable and effective antioxidant than the sulfur-containing amino acid L-cysteine. NAC gets high rankings for its ability to relieve allergies and fight viruses. It is also one of the best expectorants and mucus thinners around. NAC is a precursor of glutathione in the body and a protected sulfur-containing amino acid. Because it increases glutathione levels in the lungs, kidneys, liver and bone marrow, NAC has an anti-aging effect on the body—reducing the accumulation of age spots. N-Acetyl cysteine can also boost glutathione levels in cells. POWERFUL IMMUNE STRENGTHENING PLUS GLYCO-NUTRIENTS Glutathione functions as an antioxidant and an anti-toxin and is extremely important for the protection of major organs, the function of the immune system, and the fight against aging. It minimizes the damage caused by free radicals and is very important for the health of cells. Its major effect is inside the cells, especially within the mitochondria — the actual “power plants” of every cell in the body. Recent, extensive research has shown the direct relationship between decreased glutathione levels and the progression of many chronic diseases. The presence of glutathione is required to maintain the normal function of the immune system. You cannot have a healthy immune system without adequate levels of glutathione. We tend to believe today’s toxic environmental conditions stress our healthy and natural levels of this critical nutrient. Much research is needed, but with supplementation balance can be realized. Glutathione is known to play a critical role in the multiplication of lymphocytes (the cells that mediate specific immunity) which occurs in the development of an effective immune response. Supplemental detoxicants (helps clear toxins in your tissue where some recent studies find as many as 500 toxic substances in human tissues that did not even exist prior to 1947) become necessary as our environment becomes increasingly polluted. Our food and water sources are contaminated with chemicals since the chemical revolution of War World II where natural materials were quickly replaced with synthetics and plastics. This modern chemical revolution has created environmental toxins so powerful now the EPA says the inside of our homes is 5 times more polluted than outdoor pollution. One of our main defenses against pollutants is glutathione, which is present in the liver in high concentrations. Glutathione acts as a detoxifying agent by combining with undesirable substances and ridding the body of them through urine and bile. It is important to note that unless the Colon, Liver and Blood are also detoxified, the benefits of Glutathione as a detoxicant may be minimized. Antidepressants and other medications deplete the body and brain of glutathione. Glutathione doesn't raise dopamine levels, but it allows the dopamine in the brain to be more effective. That's not a new idea in medicine. Diabetic drugs work not by increasing insulin, but by increasing the receptors to insulin. Glutathione not only increases sensitivity to dopamine, but also to serotonin, which may explain why many of our depressed PD patients have a remarkable improvement One of the main functions of Glutathione are to enhance the immune system and Natural Biology recommends all cancer patients to seriously consider using this powerful nutrient — particularly during chemotherapy and radiation treatments. Your bodies immune activity, involving unimpeded multiplication of lymphocytes and antibody production, requires maintenance of normal levels of glutathione inside the lymphocytes. It is a powerful Antioxidant and Free Radical Scavenger. Glutathione plays a central protective role against the damaging effects of bacteria, viruses, pollutants and free radicals. It helps to regulate other key antioxidants. Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease. Glutathione is a major detoxifying agent. Another major function of glutathione is in the detoxification of foreign chemical compounds such as carcinogens and harmful metabolites Glutathione is a sulfur-containing amino acid that is an important part of the body's antioxidant defense system. Glutathione is composed of three different amino acids: cysteine, glutamic acid, and glycine. Vitamins B6 and riboflavin are critical for maintaining adequate levels of glutathione within the body. Research suggests that a variety of minerals, including copper and selenium, have a strong influence on cellular levels of glutathione. In addition, selenium is an essential part of many different forms of glutathione that exist in the body. Because of its antioxidant properties, glutathione neutralizes damaging free radicals and peroxide molecules, and recharges oxidized vitamin C so that the body may reuse it. Glutathione is required for a variety of metabolic processes. In addition, glutathione bolsters the structure of body proteins and assists in the transport of amino acids across cell membranes. Interestingly, the phytochemical limonene may boost the body's synthesis of a glutathione-containing enzyme that has antioxidant properties and helps to detoxify chemicals. Limonene is found in citrus fruit peels, cherries, green foods (celery, fennel), soy products, and wheat. Several foods contain naturally occurring glutathione, including avocado, watermelon, asparagus, grapefruit, potato, acorn squash, strawberries, orange, tomato, cantaloupe, broccoli, okra, peach, zucchini, and spinach. Glutathione also helps the liver to detoxify chemicals, such as acetaminophen (active ingredient in pain relief medication), copper, and cadmium. Scientists speculate that increasing consumption of antioxidants, such as glutathione, early in life may promote longevity and reduce chronic disease. Research is currently exploring the potential benefits of glutathione for several conditions including cancer, heart disease, memory loss, osteoarthritis, Parkinson's disease, cornea disorders, kidney dysfunction, eczema, liver disorders, poisoning by heavy metals, and immunodepression that occurs in diseases such as AIDS. Arabinogalactan represents new scientific breakthroughs in polysaccharide research called Glyco-Nutrients. They can dramatically improve immune health by improving cell to cell communication. Chronic diseases such as cancer are believed to begin when cell-to-cell communication breaks down. It has demonstrated the ability to activate immune cells involved with the body's first line of defense and to promote cytokine production, the communication and signaling pathway of immune cells. Natural Arabinogalactan Polysaccharides Supports Healthy Immune and Intestinal Function Arabinogalactans support healthy immune function, particularly macrophage activity and cytokine defense activity such as interferon gamma, tumor necrosis factor, IL-1 and IL-6. Arabinogalactans also promote the growth of the probiotic bacteria Lactobacilli and bifidobacteria — supporting a healthy intestine flora. This microflora is an additional level in supporting optimal immune function. Aloe Vera Gel Extract 200:1 is a powerful derivative from the popular cactus looking plant. People commonly squeeze the inner gel out onto burns for instant healing relief, but Aloe Vera does so much more. A lot of people use this gel in sunburn products and it is highly effective; however this polysaccharide is a powerful immune strengthening factor when taken internally. The inner gel is extracted in a powerful 200:1 strength — providing a powerful factor in our immune health formula. The research on Aloe Vera has provided a wealth of information, especially over the past ten years, and even still the mystery of Aloe is still unfolding. Aloe leaf contains over 75 nutrients and 200 active compounds, including 20 minerals, 18 amino acids, and 12 vitamins. Aloe Vera facilitates digestion, aid in blood and lymphatic circulation, as well as kidney, liver and gall bladder functions. Aloe contains at least three anti-inflammatory fatty acids that are helpful for the stomach, small intestine and colon. A newly discovered compound in aloe, acemannan, is currently being studied for its ability to strengthen the bodies natural resistance. Studies have shown acemannan to boost T-lymphocyte cells that aid the immune system. Aloe Vera has gained a tremendous following over the past few years, mainly due to its ability to relieve everything from joint pain to acting as an anti-inflammatory. One fairly recent development in the use of Aloe Vera was the discovery of mucilaginous polysaccharides (A.M.P.) and their affect on the immune system. Immune factors that provide anti-inflammatory factors are critical to over-all health because uncontrolled inflammation will lead to additional problems — thus exponentially accelerating degenerative disease possibilities. This is a major concern at Natural Biology based on our research. If you have a lot of aches and pains then you should act to get these inflammation responses under control. It is a clear sign of a weakened immune response and increased health risk. We believe Aloe Vera Gel 200:1 Extract may help in the control of inflammation response while supporting overall immune health. Additional help may be needed if you have inflammation problems, particularly multiple conditions, currently not under control. Inflammation is a clear indicator of a problem. You can also treat yourself topically with Natural Biology’s Super Blue Rx Gel; Dead Sea Salt baths; therapeutic massages; and yoga. It is one time to consider the use of ibuprofen and aspirin since reducing inflammation is even a more desired result than the possible side-effects of such per se. Nonetheless, Aloe Vera Gel Inner Leaf 200:1 Extract is a great addition to your immune health and is a proactive choice in controlling inflammation issues. Maitake mushrooms have been prized in Japanese herbology as a potent adaptogen and tonic for youth and longevity — and modern research now confirms it effective immune system support functions. Maitake Mushroom is considered the king of mushrooms and is more effective than its many cousins found in herbal formulas. The primary polysaccharide found in Maitake, beta-D-glucan, is well absorbed when taken orally and is currently under review for the prevention & treatment of cancer, and as a supportive tool for HIV infection. Laboratory studies have shown that Maitake Mushroom extract can inhibit the growth of tumors and stimulate the immune system of cancerous mice. Human clinical studies of patients with breast and colorectal cancers are currently under way in the United States. Researchers investigated a specific, high-molecular polysaccharide in Maitake called the X-fraction. They found that mice given Maitake had an increased ability to recognize glucose, and the control group had higher blood glucose levels. The researchers suggested that Maitake can reduce insulin resistance, thereby increasing insulin sensitivity. The X-fraction appears to be the active compound with anti-diabetic properties. Chlorophyllin may have antimutagenic and anticarcinogenic activities. Cholorphyllin is a natural immune strengthening agent and it naturally helps control bad body ordor.
In one in vitro test, chlorophyllin demonstrated significant inhibition of several mutagens, including cigarette smoke, coal dust and diesel emission particles. Chlorophyllin is the modified, water-soluble form of chlorophyll that has been shown to have DNA protective and antioxidant properties. It can cross cell membranes, organelle membranes, and blood brain barriers (natural chrolophyll cannot). Chrolophyllin can even enter the mitochondria where 91% of oxygen reductions occur and where the majority of free radicals are produced. Chlorophyllin quenches all major oxygen species and acts to protect mitochondria. Chlorophyllin also protects mitochondria from auto-oxidation, a reaction considered to be one of the major causes of aging. One of the more interesting uses Chlorophyllin has been used to cleanse and accelerate the healing of open wounds, to decrease the inflammation in radiation burns and, principally, to decrease odor in patients with colostomies or who were incontinent of urine or feces. Scientists have felt that chlorophyllin was capable of killing a number of bacteria and could also detoxify a number of mutagens, chemicals that could cause the sort of genetic change that is characteristic of cancer. Yet chlorophyllin has been all but forgotten by physicians in the United States, but not in the former Soviet Union, where annually clinical studies are still published concerning the effectiveness of chlorophyllin in the treatment of a number of disorders from gonorrhea to tuberculosis to leukemia. N-acetyl-glucosamine (NAG) is a form of glucosamine, one of the building blocks of joint tissue and other connective tissues. . N-Acetyl Glucosamine is the body's precursor to hyaluronic acid which is part of the synovial fluid that lubricates joints. NAG is produced in the intestinal tract via specialized cells called goblet cells which are responsible for producing your mucin (or mucosal lining). N-Acetyl Glucosamine is the superior form of glucosamine for joint and intestinal tissue. NAC is an antioxidant and a precursor to glutathione, another antioxidant that assists in the liver's detoxification pathways. NAC is the acetylated form of L-cysteine. It is a more stable and effective antioxidant than the sulfur-containing amino acid L-cysteine. NAC gets high rankings for its ability to relieve allergies and fight viruses. It is also one of the best expectorants and mucus thinners around. NAC is a precursor of glutathione in the body and a protected sulfur-containing amino acid. Because it increases glutathione levels in the lungs, kidneys, liver and bone marrow, NAC has an anti-aging effect on the body—reducing the accumulation of age spots. N-Acetyl cysteine can also boost glutathione levels in cells.
We know ginger best by the product ginger ale which is often used settle upset stomachs but it also has multiple other purposes. Ginger was always known as a medicinal plant and a spice in India and China for thousands of years. Ginger has been used by many as a remedy for the common cold. Additionally, it has also been used as an effective analgesic, anti-pyretic, anti-viral, in the treatment of hypertension, and in the prevention of atherosclerosis. Other benefits of ginger include its ability to cleanse the colon, reduce spasms and cramps, stimulate circulation, and aid metabolism. Many have used it to treat colitis, nausea, gas, indigestion, bowel disorders, morning sickness, motion sickness, vomiting, congestion, fever, and headaches. Asian medicine still uses it as a treatment for asthma, shortness of breath, water retention, earache, diarrhea, nausea and vomiting. Homeopathic practitioners even recommend it for sexual disorders. An added benefit to Ginger is that it is a strong antioxidant and effective microbial agent for sores and wounds. Ginger helps protect the gastric system by increasing the pH of stomach acid, reducing its acidity, thereby lower the rate of gastric secretions, and increasing digestive enzyme activity. Rather than blocking the feelings of nausea in the brain, it acts directly on the stomach and liver to reduce nausea and vomiting.
By providing you with a clear head and by working as a metabolism aid, Ginger Root is the perfect compliment to any diet plan. Bromelain is the name of a group of powerful protein-digesting, proteolytic enzymes that are found in the pineapple plant (Ananas comosus). It is particularly useful for reducing muscle and tissue inflammation and as a digestive aid. Bromelain is a natural blood thinner and anti-inflammatory. It works by breaking down fibrin, a blood-clotting protein that can impede good circulation and prevent tissues from draining properly. Bromelain also blocks the production of compounds that can cause swelling and pain. When inflammation is reduced, blood can move more easily to a traumatized area, easing pain and speeding healing. Quercetin is a member of the flavonoid family present in foods such as onions and blue-green algae. Quercetin stabilizes cell membranes and helps prevent free radical damage to this vulnerable part of the cell. It works best in the presence of Vitamin C. It appears to fight a host of disorders including asthma, cancer, glout, cataracts, and heart attacks. As an antioxidant, it combats the destructive "free radical" molecules that play a part in many diseases. Among people with high dietary intakes of quercetin and other major flavonoids, studies show lower rates of stomach, lung, pancreatic, and breast cancers. Quercetin inhibits the buildup of a type of blood sugar that could otherwise lead to cataract formation in the lens of the eye. In a Rotterdam Study published in the 2002 American Journal of Clinical Nutrition flavonoid intakes showed a reduced risk of heart attacks — and for women the role as a phytoestrogen can help in heart-protective benefits similar to soy. The latest findings indicate that quercetin and other flavonoids may also help to prevent heart attacks. The Rotterdam Study, published in the 2002 American Journal of Clinical Nutrition, examined the tea-drinking habits and dietary flavonoid intakes of nearly 5,000 adults in Holland. Apparently due to black tea's high flavonoid concentration, daily consumption of the brew reduced the risk of heart attack overall for tea drinkers.
And in women, a strong connection was found between high intake of dietary flavonoids and reduced risk of fatal heart attack. The researchers speculate that women's extra protection may be related to the flavonoids' role as phytoestrogens (plant estrogens), which can offer heart-protective benefits similar to those of soy. A previous study had also shown that flavonoids increased bone density in women, a known action of phytoestrogens. Quercetin, a natural anti-inflammatory, may be helpful in countering the hallmark of Crohn's disease: chronic inflammation of the gastrointestinal tract. As a flavonoid, quercetin functions as a natural anti-inflammatory, antihistamine, and possibly an inhibitor of Helicobacter pylori, the bacterium associated with stomach ulcers, which can cause recurrent heartburn. If your heartburn symptoms are persistent, you may want to take a daily combination of quercetin and flavonoids to accelerate healing.
Folic ACID Folic acid has been shown in clinical trails to have a multitude of important health benefits, including reducing the risks of colon and ovarian tumors, heart attack and stroke, and significantly reducing the risk of birth defects known as neural tube defects (spina bifida and other similar types of conditions). In a recent American Heart Association conference on hypertension (high blood pressure) researchers reported on the results of over 95,000 women who had been part of the “Nurses’ Health Study”. Folic acid intake was analyzed. It was found that in the nurses group, ages 26 to
46, those women who took more than 800 mcg of Folic acid a day reduced the risk of hypertension by 29% compared to those nurses who consumed only 200 mcg of Folic acid a day. Women ages 43 to 70 who consumed more than 800 mcg a day of Folic acid had a reduction in hypertension risk of 13%. Since it is extremely difficult to consume 800 mcg of Folic acid from diet alone, all the women in the highest Folic acid intake group took supplemental vitamins. Hypertension is a silent killer. It is a major risk factor for cerebrovascular disease, cardiovascular disease (heart attack) and renal failure. It is estimated there are approximately 50 million people in this country who have hypertension, however about 15 million of these people are undiagnosed! It used to be believed that hypertension was anything over 140/90, although more recent research has indicated that keeping blood pressure in the low normal range, around 110/60, actually reduces incidence of stroke and cardiovascular disease. In addition to Folic acid, there are other nutrients that have been shown to have beneficial effect for promoting healthy blood pressure. These nutrients include Vitamin C, Vitamin D, Vitamin E, Garlic, Calcium-Magnesium, Potassium and Coenzyme Q10 (CoQ10). A study recently published in the journal Hypertension found that daily nighttime supplementation of Melatonin had a beneficial effect on reducing the blood pressure of male patients with hypertension. Melatonin intake was shown to reduce systolic and diastolic blood pressure and improve sleep, while not affecting heart rates. ANTI AGING, AMINO ACIDS, & HGH STIMULATION L-Dopa is a naturally occuring amino acid that provides a large number of health benefits, primarily the ability to increase HGH levels as much as 400%. This helps regeneration of healthy organs including the kidneys, liver, and lungs. It promotes better sleep, less cellulite, leaner muscle mass, and improved skin conditions including less wrinkling. The most common benefit is improved focus and increased energy. Other benefits include emotional stabilizing effects and increased libido. L-Dopa is primarily known for it's conversion into dopamine. Dopamine is an essential component required for proper brain function. L-Dopa has been researched for over 50 years and requires a prescription until large concentrations were discovered in a natural alternative "MUCUNA PRURIENS.” We can all now experience the benefits of this wonderful substance. The wonder of the natural source is the body actually absorbs and utilizes a higher percentage than the prescription form. Therefore you can experience better results with smaller amounts. There are also no side effects. The 50% material used in Med Factors is the highest natural concentrations available. Restoring Human Growth Hormone (HGH) back to youthful levels is one of the most effective Anti-Aging strategies. Our natural HGH levels decline as we get older, leading to numerous physiological problems. L-Dopa restores HGH back to youthful levels, helping you look & feel years younger. L-Dopa turns into dopamine once it is digested in the body. The increased levels of dopamine stimulate the release of your natural Human Growth Hormone (HGH) from your pituitary gland. Numerous clinical studies have shown increased HGH levels of over 400% with L-Dopa. L-Dopa has been clinically proven to benefit Parkinsons, and it increases the body’s natural production of HGH — thus it is known for its anti aging qualities. These include strengthening the immune system, increasing lean muscle mass, improving mood, enhancing libido, and increasing energy levels. Glutamine is an amino acid of extreme importance and it has been shown in research to help increase HGH levels. Every cell in the body uses glutamine. Some tissue types, however, depend on glutamine much more than others. Without sufficient glutamine, the intestines atrophy (decline in healthy function) and the immune function breaks down. Hair follicles, the fetus, and unfortunately also many types of tumors also greatly depend on glutamine for energy production and DNA and RNA synthesis. In addition, glutamine serves as a nitrogen donor and a carbon donor, and is thus an important muscle-building amino acid; it also helps replenish muscle glycogen after exercise. Without sufficient glutamine, muscles begin to atrophy. Thus glutamine is essential for intestinal & immune and muscle functions. The synthesis of glutamine protects the body, and the brain in particular, from ammonia toxicity.. Glutamine users often report more energy, less fatigue and better mood. Glutamine also plays a part in maintaining proper blood glucose levels and the right pH range. The body has an exquisite mechanism for maintaining pH homeostasis. If the pH of the blood is too acidic, more glutamine is directed to the kidneys, where a certain type of glutamine results in the release of bicarbonate ions to correct acidosis. If the pH is too alkaline, more glutamine is sent to the liver, where a different kind of metabolism releases hydrogen ions to correct alkalosis. Glutamine also plays a vital part in the control of blood sugar. It helps prevent hypoglycemia, since it is easily converted to glucose when blood sugar is low. In addition, glutamine regulates the expression of certain genes, including those that govern certain protective enzymes, and helps regulate the biosynthesis of DNA and RNA. Recently it has been discovered that glutamine is important for the cardiovascular system as well.
Glutamine is critical during heavy stress, such as strenuous exercise, infectious disease, surgery, burn injury or other acute trauma leads to glutamine depletion with consequent immune dysfunction, intestinal problems and muscle wasting. People who use glutamine virtually ensure superior health of their intestinal lining. They need not worry about the "leaky gut syndrome" and all its troublesome consequences, including allergies, the "leaking out" of pathogens and possible arthritis. In fact, when it was first discovered, glutamine used to be called "intestinal permeability factor." It is by far the most important nutrient for intestinal health. Those who use NSAIDs (non-steroidal anti-inflammatories) such as ibuprofen and indomethacin may have a special need for supplemental glutamine. Fortunately, sufficient glutamine can undo the damage caused by NSAIDs, maintaining permeability at a healthy level. For heavy NSAID users, supplementing with glutamine can spell the difference between healthy gastrointestinal tract versus ulcers and the "leaky gut syndrome."
Likewise, glutamine protects the liver from the ravages of chemotherapy toxicity. But even under normal conditions, glutamine is beneficial for the liver, since it cleanses the liver of the waste products of fat metabolism, and helps prevent fatty buildup. It can aid in the treatment of early-stage cirrhosis. Once liver damage is advanced, however, glutamine cannot help since the liver can no longer metabolize it properly. People who take glutamine tend to have a healthier liver and healthier intestines, and thus better digestion and absorption of nutrients. Glutamine is the primary source of energy for the various cells of the immune system, including T cells and macrophages. Strenuous exercise, viral and bacterial infections, and stress and trauma in general cause glutamine depletion that starves the immune cells. It has recently been discovered that glutamine is an important source of fuel for the heart muscle. It is converted to glutamate, which then enters the Krebs cycle to produce ATP, our energy molecule. Glutamine can enter the Krebs cycle and serve as a non-carbohydrate source of energy. In fact, this is the main way it usually contributes to the production of energy. However, if the blood sugar is low (hypoglycemia), glutamine is readily catabolized (broken down) in the liver to provide more glucose. Together with alanine, glycine, serine and threonine, glutamine is an important "gluconeogenic" amino acid, in fact the primary one. This production of glucose from glutamine takes place mainly in the liver. Recently, however, it has been discovered that the kidneys can contribute as much as 25% to whole-body glucose production, a phenomenon that occurs only during hypoglycemia. Actually this is not surprising, since the kidneys are especially equipped to process glutamine due to its importance in the detoxification of ammonia. Providing abundant glutamine through diet and supplementation means that less muscle tissue (if any) will be broken down to provide glucose. This is of great importance to people on calorie-restricted diets, whose great problem is losing muscle mass more so than fatty tissue. Since it is the metabolically active muscle mass that helps keep us slender (not to mention strong and fit), extra glutamine can help dieters lose girth around the waist while preserving muscle mass. Considering the effectiveness of glutamine in combating hypoglycemia, it is no wonder that alternative medicine recommends it for the purpose of eliminating sugar cravings, and alcohol cravings in the fight against alcoholism (many alcoholics appear to suffer from hypoglycemia). Diabetics, however, need to exercise caution, since they have an abnormal glutamine metabolism. A much higher percentage of their glutamine is broken down for the production of glucose by the liver and the kidneys, a process called glutamine gluconeogenesis. This increased production of glucose from glutamine (and also from alanine, an amino acid in the same family) is probably related to the diabetes-related excess levels of the serum glucose-raising pancreatic hormone called glucagon. True, this excessive breakdown of glutamine into glucose in diabetes occurs without any supplementation, since the muscle and the fatty tissue release so much glutamine in response to the endocrine pathology. Diabetics also show other enzymatic abnormalities in relation to glutamine, including poor function of the retinal glia (glia are cells that have various supportive functions in the nervous system, including detoxifying ammonia through the production of glutamine). Thus the diabetic retina is prone to damage through glutamate excitotoxicity, since the glia are not converting enough glutamate to glutamine. While a plausible argument could be made for the benefits of glutamine even for diabetics-sparing of muscle mass, improved intestinal function, enhanced immune response-caution must be urged. A diabetic considering taking any amino acids should discuss the matter with his/her physician. The use of high doses of antioxidants, including vitamin E and various polyphenols, should be beneficial, as well as supplementation with taurine. Taurine is the one amino acid that seems to be very helpful to diabetics. We have already said that glutamine is heavily used by all rapidly dividing cells. This includes many types of tumors. Thus is would seem plausible to argue that this is certainly the amino acid that cancer patients should avoid. In reality, however, glutamine is frequently used as an adjuvant treatment of advanced cancer. It has been shown to prolong survival by slowing down catabolic wasting. In addition, since low immune function is a hallmark of cancer, glutamine is considered beneficial for the depleted immune system. It helps preserve intestinal function as well. Both clinical practice and animal studies suggest that glutamine can be given to cancer patients without stimulating tumor growth or metastasis. Nevertheless, the use of any amino acids in cancer remains controversial, and patients are urged to consult with their physicians first. The most fascinating findings regarding glutamine and cancer, however, suggest that glutamine may be another weapon against breast cancer. N-Acetyl Tyrosine supports brain function by improving the synthesis of the catecholamines norepinephrine and dopamine (neurotransmitters). N-Acetyl Tyrosine supports brain function and a good mood by improving the synthesis of key neurotransmitters. The body produces neurotransmitters to facilitate communication within the nervous system. l-Lysine is an essential amino acid (a protein building block) that cannot be produced by the body from other nutrients. It helps ensure adequate absorption of calcium and the formation of collagen for bone, cartilage and connective tissue. Lysine strengthens circulation and helps the immune system manufacture antibodies. It also helps control the body’s acid/alkaline balance, influences the pineal and mammary glands and plays a role in gallbladder function. It is necessary for all amino acid assimilation and assists in the storage of fats. ENERGY, VITALITY, & MOOD NUTRIENTS DMAE steps up production of brain chemicals essential for short-term memory, concentration, and learning capacity. DMAE may aid in the treatment of ADHD and other disorders affecting the brain and central nervous system. DMAE is sometimes referred to as a "cholinergic" because it is thought to increase levels of the neurotransmitter acetylcholine, one of the chemicals in the brain that enhances mental powers. The possible memory-boosting effects of DMAE may help with the ordinary memory lapses that occur with normal aging. Many nutritionally oriented physicians prescribe DMAE as a mental enhancer. Although rigorous studies are lacking, some people who have tried DMAE report better memory (especially short-term memory), as well as improved concentration, focus, mental clarity, and sleep. DMAE increases the body's production of Energy and persons using DMAE subjectively report increases in their levels of Energy. DMAE reduces Apathy and increases Motivation in persons afflicted with Depression. DMAE users experience a sounder Sleep [after 6 weeks subjects reported waking earlier and having a clearer mind upon waking]. DMAE increases Attention Span [after 6 weeks of DMAE supplementation students were able to concentrate at lectures better and were able to study and concentrate on exams better]. The purest form of this extract comes from the mountains in Siberia. This adaptogen is not well-known in the United States but is one of the more fascinating plant species in the world today. The extraordinary medicinal benefits include increased longevity, physical endurance, decrease depression, elevate mood, improve mental alertness, and support hormonal health. The overall best use is general vitality and increased energy levels. Ginko Biloba is one of the most well-researched herbs in the world in the last 30 years with over 300 studies giving clinical evidence to its benefits to human health. It is realized today as the bran’s tonic for enhancing memory because of its positive effects on the vascular system, especially in the cerebellum. It has been used to treat vertigo & tinnitus (ringing in the ears). Ginkgo may help counteract the effects of aging, including mental fatigue and a lack of energy. Ginkgo works by increasing blood flow to the brain and throughout the body's network of blood vessels that supply blood and oxygen to the organ systems. It increases metabolism efficiency, regulates neurotransmitters, and boosts oxygen levels in the brain which uses 20% of the body's oxygen. Benefits of enhanced circulation in the brain include improved short and long term memory, increased reaction time and improved mental clarity. Ginkgo is often used to treat elderly persons with Alzheimer's and other symptoms of cerebral insufficiency. Cerebral insufficiency is a general term for a collection of symptoms that include difficulties of concentration and memory, absentmindedness, confusion, lack of energy, depressive mood, anxiety, dizziness, tinnitus, and headache. Ginkgo constituents are beneficial for a variety of imbalances and deterioration in the brain and body. Standardized ginkgo extract inhibits platelet activity factor (PAF), which is a common allergen in the body. Physical stress, and poor quality food can overstimulate PAF production; in other words, blood clotting. Excessive PAF can help cause cardiovascular disease, brain damage, hearing disorders and other immune and inflammatory diseases. Ginkgo has been used to relieve tension and anxiety and improve mental alertness, elevate mood and restore energy. Ginkgo has two groups of active substances, flavonoids and terpene lactones, including ginkgolides A, B, and C, bilobalide, quercetin, and kaempferol. The ginkgolides have been shown to control allergic inflammation, anaphylactic shock and asthma. Ginkgo also acts as a powerful antioxidant and contributes to the oxidation of free radicals which are believed to contribute to premature aging and dementia. Antioxidants also protect the eyes, cardiovascular system and central nervous system. Ginkgo may also help control the transformation of cholesterol to plaque associated with the hardening of arteries, and can relax constricted blood vessels. The herb has been used in treatment of other circulation-related disorders such as diabetic peripheral vascular disease, Raynaud's syndrome, hemorrhoids and varicose veins. It can also aid in the treatment of insufficient circulation and complications from stroke and skull injuries. Ginkgo's beneficial effects on the circulatory system also can be of benefit in the treatment of eye and ear disorders. Studies have confirmed that ginkgo increases blood flow to the retina, and can slow retinal deterioration resulting in an increase of visual acuity. In clinical tests ginkgo has improved hearing loss in the elderly. It also improves circulation in the extremities relieving cold hands and feet, swelling in the limbs and chronic arterial blockage. Among other things, ginkgo is being investigated as a potential treatment to prevent the rejection of transplanted organs, as a treatment for asthma and for toxic shock syndrome Malic acid is a naturally occurring compound that plays a role in the complex process of deriving adenosine triphosphate (ATP; the energy currency that runs the body) from food. People with fibromyalgia should use Malic acid with Magnesium. It helps improve muscle comfort and promotes higher energy levels. Malic Acid is being researched increasingly as a excellent supplement for people suffering from FMS and CFS because it helps with their chronic fatigue. Malic Acid is also useful for improving calcium absorption. Inositol, an essential component of the phospholipids that make up cellular membranes. Recent research indicates that inositol helps establish healthy cell membranes, which facilitate nerve impulses. Biochemical functions of phosphoinositol in cell membranes include regulation of cellular responses to external stimuli as well as mediation of enzyme activity. It is part of all cell membranes in the body, and plays a role in helping the liver process fats as well as contributing to the function of muscles and nerves.
One clinical study showed that subjects had therapeutic results similar to common antidepressant drugs, but with no unwanted side effects. In addition, it can participate in the action of serotonin, a neurotransmitter whose levels in the brain are known to be a factor in depression and anxiety. Preliminary studies suggest that it’s more useful than placebo for such conditions as Attention Deficit Disorder, Bulimia Nervosa and Binge Eating, too. Studies have shown it’s at least as effective as commonly used serotonin selective reuptake inhibitors (SSRIs). Given the success of this supplement for some central nervous system disorders, its use for pain control has been recently evaluated as well. Choline is a vitamin like compound which is an essential part of the human diet as it is used by the body to produce acetylcholine. Choline is one of the important brain chemicals involved in memory as well as essential for the process of breaking down fat for energy. It also helps in the production of lipotropic agents which converts fats into useful products and aids in the production of HDL (good) cholesterol. Choline is necessary for the structure and function of all cells and is crucial for sustaining life. Choline is an essential nutrient required by the body to make several important compounds necessary for healthy cell membranes. Choline helps form phosphatidylcholine, the primary phospholipid of cell membranes. Choline is also the precursor to acetylcholine, one of the important brain chemicals involved in memory. A major use of choline in the body is the formation of betaine, an important methyl donor. And, like phosphatidylcholine, choline may be helpful in some liver diseases, manic conditions, cognitive disorders, tardive dyskinesia and, possibly, some cancers. The Food and Nutrition Board of the National Academy of Sciences is impressed enough with research to date that it has recently recommended that pregnant and nursing women increase their intake of choline. Marathon runners are experimenting with choline supplementation during the final stages of the race to boost declining energy levels which have been associated with declining choline levels. This is a critical metabolite in the Krebs Cycle which boost the production of ATP energy potential, but it also increases muscle cell’s production of creatine phosphate, another high energy chemical. It’s primary role however is to boost energy levels — thus providing essential nutrients for elevating vitality. PABA appears to be a component of folic acid, a member of the B family of vitamins. It plays a role in breaking down and using proteins, and in forming red blood cells.
When PABA is in short supply fatigue, irritability, nervousness and depression might manifest itself as well as constipation. Weeping eczema PABA is used to improve the protein used in the body, it relates to red blood cell formation as well as assisting the manufacture of folic acid in the intestines. Para-aminobenzoic acid is used in sunscreen preparations since it can help protect the skin against ultra-violet radiation. PABA also assists with breaking down of protein, the formation of red blood cells and maintaining intestinal flora. Research indicates a possible role for PABA in treating Peyronie's disease (a disorder of the penis that affects erections). It has also been examined--though not always with success--for aiding skin changes associated with scleroderma (an autoimmune disorder), pemphigus (a severe blistering of the skin), and vitiligo (a disorder that causes discoloration of the skin). It has been linked to hair growth as well as reversing the graying of hair, but these results are disappointing. Most people will also recognize PABA as an ingredient in sunscreen lotions, where it has been shown to protect the skin by blocking damaging ultraviolet rays. However, in recent years PABA's popularity as a sunscreen has declined due to reports that it can irritate the skin and cause allergic reactions in some people. This does not seem to be the case when taken orally. PABA can interfere with the absorption of sulfa antibiotics. SUPPORTING NUTRIENTS Bioperine is a standardized extract from the fruits of Piper nigrum L. (black pepper) or Piper longum L. (long pepper). The primary benefit of Bioperine in a supplement is it improves the absorption rate of all other ingredients. It contains a minimum piperine content of 95% compared to the 3-9% and 3-5% found in raw forms of Piper nigrum and Piper longum, respectively. Supplements in capsules require filler material which is usually rice bran, but Med Factors uses Soy Protien Isolates which provide all the properties of Soy Isoflavones — and they are present in large quantities because filler can represent up to 25% of the total masm weight of a supplement. Soy Isoflavones can prevent illness and promote good health. Isoflavones are a class of phytochemicals, which are compounds found only in plants (phyto means plant). They are also a type of phytoestrogen, or plant hormone, that resembles human estrogen in chemical structure yet are weaker. Isoflavones show tremendous potential to fight disease on several fronts — breast cancer in women and prostrate cancer in men. They have been shown to help prevent the buildup of arterial plaque, which reduces the risk of coronary heart disease and stroke. Isoflavones may help reduce breast cancer by blocking the cancer-causing effects of human estrogen. They may also prevent prostate cancer by hindering cell growth. Isoflavones can fight osteoporosis by stimulating bone formation and inhibiting bone resorption. They may even relieve some menopausal symptoms as well. Soy isoflavones have antioxidant properties which protect the cardiovascular system from oxidation of LDL (the bad) cholesterol. Oxidized LDL cholesterol accumulates in the arteries as patches of fatty buildup which blocks the flow of blood, resulting in atherosclerosis. Genistein inhibits the growth of cells that form this artery clogging plaque. Arteries damaged by atherosclerosis usually form blood clots. This can lead to a heart attack if the clot goes to the heart, or a stroke if it goes to the brain. Being a weak form of estrogen, isoflavones can compete at estrogen receptor sites, blocking the stronger version naturally produced by the body from exerting its full effect. Since high blood levels of estrogen are an established risk factor for breast cancer; weaker forms of estrogen may provide protection against this disease. Genistein has been found to hinder breast cancer as well as prostate cancer. Results from a new University of California study show that genistein slowed prostate cancer growth and caused prostate cancer cells to die. It acts against cancer cells in a way similar to many common cancer-treating drugs. Isoflavones also play an important role in protecting and maintaining strong and healthy bones. Isoflavones also play an important role in protecting and maintaining strong and healthy bones. Evidence shows that genistein and daidzein prevent bones from breaking down. Independent studies conducted at the University of Illinois and the University of Hong Kong concluded that consuming soy isoflavones can increase bone mineral content and bone density. Another study at the University of Texas suggested that isoflavones may also stimulate bone formation. By preserving bone health, increasing bone mass and inducing bone turnover, researchers noted the potential role of soy isoflavones in preventing, and possibly even reversing, the effects of osteoporosis.
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