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  Magnesium Citrate 1000 Grams
 
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Product Code: MAGNESIUMCITRATE1000
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DESCRIPTION
 
Natural Biology's Magnesium Citrate is USP grade and each bag contains 1000 Grams or 2.2 pounds = 1 Kilo. 
PRODUCT DESCRIPTION
Magnesium citrate is the result of the chemical combination of magnesium carbonate and citric acid. It is known as one of the most absorbable forms of magnesium, an essential mineral that plays a critical role in more than 300 metabolic reactions in the body. Magnesium is required in protein, fat and nucleic acid synthesis. It also helps the body use glucose, and it is a key player in the body’s energy transport system. Magnesium is also necessary in inhibiting muscle contractions and blood clotting. Because of this, magnesium citrate can be used as a muscle relaxant. Magnesium is also helpful in maintaining tooth enamel, and it is of paramount importance to the proper functioning of the immune system. 

Additionally, Magnesium is also important to heart function. People who do not have enough magnesium manifest noticeable changes in the walls of their arteries and capillaries, which choke and compress in the absence of the mineral. This can result to increased blood pressure which could later on develop as a full blown cardiovascular disease. As such, supplements of magnesium citrate can prevent hypertension and heart disease. Food sources of magnesium include nuts, whole grains, legumes, tofu, green leafy vegetables, wheat bran, soybean flour, almonds, cashews, pine nuts, and black walnuts, and seafood. In the average diet, these foods are often not consumed in adequate amounts to meet the body’s need for magnesium. In such cases of deficiencies, taking supplements of magnesium citrate, especially when conditions related to magnesium deficiency are present. These conditions may have symptoms such as muscle weakness, mitral valve proplapse, ADHD, depression, anxiety, constipation, and asthma. 

Magnesium citrate may also be a beneficial and welcome addition in the supplement regimen for specific groups that are at risk of magnesium deficiency, particularly the elderly, diabetics, and those who rely on diuretics. Women who use oral contraceptives may benefit from extra magnesium as well. In addition, symptoms of premenstrual syndrome (PMS) respond to supplements of magnesium citrate because of the mineral’s calming effect on the body. Because calcium and magnesium work synergistically, magnesium citrate supplements should be taken in doses that equal a one to two (1:2) ratio of magnesium to calcium respectively. For example, an individual taking 500 mg of magnesium citrate should take a corresponding 1000 mg of calcium. Magnesium citrate functions as a mild laxative as well. While this is often the desired outcome, it can also be an unwanted side effect of taking magnesium citrate supplements. Taking adequate amounts of calcium in addition to magnesium citrate can counter this effect. 

What is Magnesium Citrate used for and who uses it?

Magnesium is a mineral required by every cell of your body. About half of the body's magnesium stores are found inside cells of body tissues and organs, and half are combined with calcium and phosphorus in bone. Only one percent of the body’s magnesium is found in blood. Our body works very hard to keep blood levels of it constant. Magnesium is important for over 300 biochemical reactions in the body. It keeps normal muscle and nerve function, maintains and stabilizes heart rhythm, and it strengthens bones. It is also crucial in energy metabolism and protein synthesis. Magnesium Citrate is used to clean stool from the intestines before surgery or certain bowel procedures such as colonoscopy, radiography, etc. It may also be used for relief from constipation. Magnesium citrate is a saline laxative that works by increasing fluid in the small intestine. It typically results in a bowel movement within 30 minutes to 3 hours. 

Magnesium has been used as a treatment for other conditions as well, including Raynaud’s disease, skeletal muscle spasm from injury or trauma, gangrene, epilepsy, spastic colon, dry skin, nervous irritability, and lead toxicity. Magnesium supplementation may be indicated for persons with alcoholism. This is because low blood levels of magnesium occur in 30% to 60% of alcoholics, and in nearly 90% of patients experiencing alcohol withdrawal. Others who need supplemental magnesium are individuals with chronic malabsorptive problems such as Crohn's disease, gluten sensitive enteropathy, regional enteritis, and intestinal surgery may lose magnesium through diarrhea and fat malabsorption. Also, individuals with chronically low blood levels of potassium and calcium may have an underlying problem with magnesium deficiency. With the help of Magnesium supplements, the potassium and calcium deficiencies can be restored to normal and optimal levels. Older adults also need supplemental magnesium since they are at an increased risk for magnesium deficiency. Add to that the fact that seniors are more likely to be taking drugs that interact with magnesium, this combination of factors makes older adults more susceptible to magnesium deficiency. As such it is very important for older adults to consume recommended amounts of dietary magnesium. 

How pure is your Magnesium Citrate?

Magnesium citrate is 16% elemental magnesium. You will receive a sealed  polyethylene bag containing this salt of magnesium and citric acid. It contains no fillers, taste additives, or anti-caking agents. While this macro-mineral is easily obtained from many dietary sources, magnesium deficiencies are extremely common for many Americans. Alcohol consumption, the presence of fluoride, and the consumption of certain foods either decrease its absorption or increase our need for magnesium. Magnesium is not only one of the key nutrients required in both calcium utilization and protein synthesis, but it also plays a tremendous role in virtually every enzymatic reaction in our body. For these reasons, supplementation may be necessary. 

What are some of the common effects and benefits of Magnesium Citrate?

Magnesium has been found effective in preventing formation of blood clots, lowering blood pressure, preventing diabetes-related complications, maintaining bone strength, and contributing to longer and healthier life by reducing the risk of heart disease and by limiting the effects of free radical damage. Magnesium is also a mineral essential to a wide variety of body processes, including energy production, protein formation, DNA production, and nerve conduction. It maintains normal levels of potassium, phosphorus, calcium, adrenaline and insulin, and also helps in keeping the bones and the heart strong and healthy. 

Magnesium stabilizes and relaxes the heart muscles to maintain a regular heartbeat, thus preventing sudden spikes in blood pressure. In fact, magnesium can be used to treat high blood pressure, angina, and arrhythmia. If given right away after a heart attack and for the succeeding weeks, magnesium has been demonstrated to speed recovery by decreasing the incidence of dangerous arrhythmias. Magnesium also protects the heart by raising HDL (good) cholesterol levels and also by inhibiting the aggregation (clumping) of red blood cells, which can lead to the formation of blood clots. 

Magnesium is essential for the development and maintenance of healthy bones. If taken in relatively high amounts, it works synergistically with calcium and vitamin D to strengthen bones and prevent osteoporosis. Magnesium is also sometimes prescribed for treatment of migraines, asthma, and diabetes. Individuals with poorly controlled diabetes may benefit from magnesium supplements because of increased magnesium loss in urine associated with hyperglycemia. People with diabetes often have low magnesium levels, and there’s some evidence that 200 to 300 milligrams of magnesium each day could help prevent and treat this disease. To help dissolve kidney stones, Magnesium is usually taken in combination with vitamin B6 (pyridoxine). 

What is the daily suggested dose and preparation of Magnesium Citrate?

The oral magnesium citrate supplement is a salt, or a substance formed when an acid reacts with an alkali. Magnesium is an alkali mineral (and also a metal) and citric acid is the acid. Elemental magnesium refers to the amount of magnesium in each compound. The amount of elemental magnesium in a compound influence the effectiveness of the magnesium supplement. 

Because magnesium citrate is 16% elemental magnesium, taking 100 milligrams of magnesium citrate powder in a single dose will yield 16 milligrams elemental magnesium.  

Recommended Dietary Allowances for magnesium for children and adults (mg/day): 
Children 1 to 3 years: 80 mg 
Children 4 to 8 years: 130 mg 
Children 9 to 13 years: 240 mg 
Adolescent and adult males 270–400 mg 
Adolescent and adult females 280–300 mg 
Pregnant females 320 mg 
Breast-feeding females 340–355 mg 

There is insufficient information on magnesium to establish a RDA for infants. Magnesium is generally recommended in small doses 3 to 6 times throughout the day, depending upon individual needs with a full glass of water with each dose to avoid diarrhea. For the treatment of specific medical conditions some physicians will occasionally recommend much higher doses than this so before you consider taking higher doses you should talk to your physician or pharmacist about Magnesium Carbonate dosing and consider their guidance before taking larger doses of this product. Before taking any kind of medicine, check with your doctor to ensure that the supplement you want to take is right for you. You may be allergic or you may have a sensitive stomach which may raise the need for special instruction as far as dosage goes. 

Precautions and Potential side effects of Magnesium Citrate

Dietary magnesium does not pose a health risk, however very high doses of magnesium supplements, which may be added to laxatives, can promote adverse effects such as diarrhea. Magnesium toxicity is more often associated with kidney failure, when the kidney loses the ability to remove excess magnesium. Very large doses of laxatives also have been associated with magnesium toxicity, even with normal kidney function. The elderly are at risk of magnesium toxicity because kidney function declines with age and they are more likely to take magnesium-containing laxatives and antacids. Signs of excess magnesium can be similar to magnesium deficiency and include mental status changes, nausea, diarrhea, appetite loss, muscle weakness, difficulty breathing, extremely low blood pressure, and irregular heartbeat. 

Natural Biology's information about magnesium citrate is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care. 

References & Further Research

Magnesium in cardiovascular and other disorders 
The physiological role and metabolism of magnesium, the causes of magnesium deficiency, clinical data on the benefits of magnesium supplementation, and the management of magnesium deficiency are discussed. 

Is low magnesium concentration a risk factor for coronary heart disease? The Atherosclerosis Risk in Communities (ARIC) Study 
Hypomagnesemia has been hypothesized to play a role in coronary heart disease (CHD), but few prospective epidemiologic studies have been conducted. Overall data and findings fom the research method suggest that low magnesium concentration may contribute to the pathogenesis of coronary atherosclerosis or acute thrombosis. 

Effects of Oral Magnesium Therapy on Exercise Tolerance, Exercise-Induced Chest Pain, and Quality of Life in Patients With Coronary Artery Disease 
Previous studies have demonstrated that magnesium supplementation improves endothelial function in patients with coronary artery disease (CAD). However, the impact on clinical outcomes, such as exercise-induced chest pain, exercise tolerance, and quality of life, has not been established. In a multicenter, multinational, prospective, randomized, double-blind and placebo-controlled trial, 187 patients with CAD were randomized to receive either oral magnesium 15 mmol twice daily Overall data and findings suggest that oral magnesium supplementation in patients with CAD for 6 months results in a significant improvement in exercise tolerance, exercise-induced chest pain, and quality of life, suggesting a potential mechanism whereby magnesium could beneficially alter outcomes in patients with CAD. 

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