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Brain Rocket Special Report

Quality + Purity + Potency + Results = Brain Rocket

In this special report we talk primarily about Brain Rocket but we also discuss other ingredients used at Natural Biology which support brain health, particularly those ingredients that are supported by a wealth of research. Natural Biology uses meta-analysis to congregate research and discover useful averages and then expands our research into the orthomolecular model.
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Brain Rocket is scientifically engineered to quickly increase the speed of neural transmission and information processing (perceptual focus, memory storage and recall), with a prolonged effect of 2-6 hours following each dosage. Active compounds specially prepared in the exclusive Brain Rocket Formula are supported by clinical research and have been cited in over 4,050 scientific studies.

Brain Rocket consists of a select group of compounds proven safe in the food supply over a 10-year period, and every constituent ingredient has been designated as part of the Generally Recognized as Safe (GRAS) list by the US government.

Brain Rocket has been manufactured for safety in a fully temperature-controlled USA GMP & FDA-inspected facility that ensures purity and accuracy of materials through inspection and evaluation at every step of production and packaging. Product purity & potency is verified through independent 3rd party analysis, and Brain Rocket is specially produced to meet or exceed United States Pharmacopeia (USP) standards.

Background

Natural Biology Labs has been at the front of brain health since 2001. We were way ahead of the FDA when our research determined most Americans had a Omega 3 deficiency and this alone can affect mental health – in particular those prone to depression. Omega 3s are critical to brain health unless you eat a diet high in omega 3 fish and plant life – avocado is one of the best. We also have written dozens of meta- analysis reports about the value of amino acids in mental health – and we recommend whey protein as a great source of amino acids for the average person; however, this is just the beginning of an exciting field – how supplements can dramatically improve brain health.

Natural Biology has provided products with DHEA, pregnenolone, ginko biloba, DMAE, polypeptide complexes, and vinpocentine through the years – and we have included many of these ingredients in our multi-functional products like Med Factors, Zolamay, OxyAGE, and now most notably EVEREST Earth & Sea Formula. EVEREST Earth & Sea formula along with an Omega 3 supplements offers an incredible foundation for brain health – and we hear from customers all the time who tells us how this protocol has rejuvenated their minds and bodies.

There are also micro-nutrients like resveratrol that we are just beginning to understand and there is little doubt that it has a positive benefit upon the longevity gene – and thus aids in mental health. The argument for good supplements and mental health has never been better.

Today, the pressures at all ages require us to be mentally sharp. We have followed with great interest brain supplements for the past 9 years – studying products and figuring out what works and what does not. We were not too satisfied that any company had made a truly great brain supplement. The main reason is they cut corners in their formulations to save cost and some just base their products on supplement folklore and not on recent clinical studies and research.

Our research determined a cognitive enhancer should worked quickly – lasted approx. 4 hours – and could be taken prior to any activity that requires increased focus, that was safe and effective without any side-effects. Thus – Brain Rocket was conceptualized.

Being mentally sharp, staying focused, recalling your memory, being able to concentrate – all have one thing in common “brain speed” – the ability to “be in the zone.” Ask any golfer who scores better than their normal average and they will tell you they found a zone that transcended normal. Ask a great golf who falls apart and they will tell you they lost their focus. There is a special mind/body connection we all have. Riding a motorcycle requires focus and a keen sense of your evolving environment. Students require long periods of concentration. Whatever demands life throws at you at school, work, or play – Brain Rocket gives you the edge. Here’s how!

Research Report - Cerebral Revitalizer

Over 300 Scientific Studies validate the ingredients in Brain Rocket at these potencies

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and particularly at these purity levels...

BIOVINCA VINPOCETINE: The common periwinkle plant has long been used all over the world as a folk remedy for a variety of diseases such as diabetes, wasp stings, coughs, colds, eye infections, lung congestion, and especially for headaches. Scientific research has shown that this plant can indeed have a real effect on physical ailments. In the 1950s, western researchers examined the periwinkle plant and found that it contains at least 70 useful alkaloids, with one of these, vincamine, being identified as a potent cerebral revitalizer.

In the past few decades, over 300 scientific papers have been published on vincamine and its actions on animal models as well as humans. Vincamine has been found to be a cerebral vasodilator, a substance that increases blood flow to the brain. In testing, it was found that vincamine increases oxygen utilization and dilates blood vessels in the brain.

For years the cerebral vasodilating action of vinpocetine has been used in Europe to relieve a number of symptoms associated with insufficient blood flow to the brain, including vertigo, difficulty in sleeping, mood changes, depression, hearing problems, high blood pressure, and lack of blood flow to the eyes. Most commonly, it has been used to improve memory defects and concentration problems. Vincamine is a nootropic, a chemical that increases brain function without side effects. In addition to their popular use as "smart drugs" that improve memory and concentration, it has been suggested that routine consumption of nootropics can minimize damage to the brain and the natural deterioration of brain functions.

In clinical studies, Vincamine has been used to treat the loss or impairment of mental functions, the effects of stroke, age-related cerebrovascular disease, and tinnitus. The results of an Austrian study released in 1996 by the Karl Franzens University of Graz

showed that dementia patients treated with vinpocetine scored significantly higher in four cognitive function tests than those treated with placebo. An Italian study found that when treated with vincamine, 828 elderly patients from 11 hospitals who had age- related cerebrovascular insufficiencies showed long-term improvement in mental function.

Natural Biology’s BioVincaTM is an all-natural plant extract containing 98% vipocetine Brain Rocket is a smart alternative to synthetic “Smart Drugs.”

The alkaloids of the periwinkle plant have a long history of healing properties and vincamine's future as a memory, concentration, and cognitive enhancer will make it a popular item with the public.

Essayed 98% of Purity

BioVinca is a highly specialized form of Vinpocentine that is processed from the periwinkle plant to an amazing 98% essay of purity. Taken in 30mg increments (3-5 times daily) every 4 hours – there is an impressive amount of meta-analysis and clinical research that demonstrates how this bio-active micronutrient increases oxygen flow to the brain. BioVinca at these potencies and purities along with the special cognitive enhancers in Brain Rocket – provide a comprehensive and effective formula for increasing brain speed – thus improved focus, memory, concentration, and organizational skills.

Cerebral Vasodilator for all Adults

Vinpocetine is a cerebral vasodilator, a substance that improves blood flow preferentially to the brain. Vinpocetine has been shown to do this by altering the rheological properties of blood. This makes vinpocetine of particular therapeutic use in treating a myriad of illnesses associated with insufficient blood flow to the brain. In addition, vinpocetine is a dependent phosphodiesterase inhibitor. Phosphodiesterase is responsible for breaking down ATP, the primary energy “currency” of all cells. As this phosphodiesterase inhibition is specific to the brain, these results in a localized increase in energy available to neurons.

Brain Rocket is also a Nootropic

In addition, vinpocetine has been found to be a nootropic, a substance that improves cognitive function in healthy humans. Alone among natural supplements, vinpocetine has been shown to improve short-term memory in healthy volunteers.

Vinpocetine has received quite a lot of attention from the scientific community: a simple MEDLINE search turns up over 150 studies on vinpocetine published in medical journals. Vinpocetine has also received much attention in the popular press, including an article in the Wall Street Journal.

With the approval of vinpocetine as a dietary supplement by the FDA (July, 1999), and introduction of vinpocetine products by the largest manufacturers in the dietary supplement industry, the demand of vinpocetine by consumers is sure to drastically increase.

BioVinca TM is the only vinpocetine product that has been clinically-studied. All of the research collected here was performed using BioVincaTM (known as Cavinton® in Europe). This product is manufactured in Europe in our GMP facility that is registered with the FDA, and is in constant inventory in our ISO9002-certified lab. Every batch of BioVinca TM undergoes the NutriPrintTM quality assurance system, which includes over thirty QC tests at the manufacturing facility, following a European Pharmacopiae- designated regimen.

Brain Rocket for Athletes

We can confirm that none of the ingredients listed on the label as included in Brain Rocket appear on the World Anti-Doping Code (World Code) or International Olympic Committee (IOC) Banned Substance lists.

We have gone to great lengths to give athletes confidence in Brain Rocket, and the product has now been fully tested under the Australian Sports Drug Agency (ASDA) Supplements Information Scheme.

The Challenges of Aging

Increasing life span brings along the problems of aging, including intellectual decline, brain fog, and memory loss. Perhaps the most compelling new brain supplements in the U.S. nutraceutical market is BioVincaTM. BioVincaTM vinpocetine is a powerful memory enhancer derived from the lesser periwinkle (Vinca minor L.). Vinpocetine has been found to increase blood flow and increase glucose metabolism in human brains.

Vinpocetine carries an impressive body of solid scientific evidence backing claims of cognitive enhancement in humans. Indeed, vinpocetine is the only mental dietary supplement for which a direct mechanism of action has been proposed and scientifically verified.

MECHANISM OF ACTION

Vinpocetine, the active constituent of BioVincaTM, has been widely studied in humans and on animal models ( VP 1 – VP 23). Of particular interest is the observed

ability of vinpocetine to increase short-term memory and increase critical reaction time in healthy volunteers (VP 1).

BioVincaTM increases blood flow to the brain. It accomplishes this in two complementary ways:

1) Reduction in flow resistance of cerebral vessels (VP 17).

2) Improve the rheological properties of blood through the inhibition of platelet aggregation and by increasing the deformability of red blood cells of erythrocytes (VP 14). As a result, BioVinca TM reduces blood viscosity and enhances microcirculation.

3) Inhibit the enzyme phosphodiesterase. Phosphodiesterase (see figure below) is the enzyme responsible for breaking down the molecule adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and adenosine monophosphate (AMP). ATP is the primary energy “currency” of all biochemical reactions. Inhibiting phosphodiesterase activity in the brain increases the levels of ATP in cells and hence increases the amount of energy available to neurons.

TOXICITY

As a true nootropic, the effects of BioVinca TM are confined to the brain. Accordingly, toxicity is very low. Indeed, vinpocetine is much less toxic than other commonly- consumed alkaloids of similar size and bioavailability (e.g., caffeine,theobromine).

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CHILDREN: Can children use Brain Rocket?

If you are reviewing this product for potential use by a son or daughter, we advise that you first test the product yourself to gauge personal response, and then speak with a physician about potential applications for your child.

If you are examining this product for use with a high school-level or older athlete/ student, the product may be used if the athlete is able to follow product directions properly. Student’s age 16-18 who have normal development should never take more than 1 capsule per day.

As a general policy, we do not recommend this product for children or pre-adolescents under the age of 18. This is not due to any particular health risk, but because we prefer to minimize the likelihood of parental overuses, which is all too common, particularly with younger students. We would take the same precaution if our product were Vitamin C.

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Brain Rocket is not intended as a treatment for ADD, ADHD, or any other medical condition. Do not purchase any non-prescription product claimed or implied to treat such conditions, as the affiliated companies are in direct violation of FDA regulations and federal law.

If you have a child with ADD, ADHD, or other learning disabilities, we highly recommend you consult a physician before giving your child any prescription and/or natural supplement for treatment.

Inositol – Second Messenger for the Brain

Inositol is a direct precursor of phospholipids which are a major component of cellular membranes. It helps to maintain proper electrical energy and nutrient transfer across the cell membrane. As a component of lecithin, Inositol helps to prevent high cholesterol and the hardening of the arteries caused by cholesterol buildup. It is also helpful in promoting healthy hair and the prevention of eczema.

Inositol is a simple polyol precursor in a second messenger system important in the brain. Cerebrospinal fluid inositol has been reported as decreased in depression. Inositol plays an important part in the health of cell membranes especially the specialized cells in the brain, bone marrow, eyes and intestines. The function of the cell membranes is to regulate the contents of the cells, which makes effective functioning possible.

Inositol is said to promote healthy hair, hair growth, and helps in controlling estrogen levels and may assist in preventing breast lumps. It may also be of benefit in reducing blood cholesterol levels. It has therapeutic effects in the spectrum of illness responsive to serotonin selective re-uptake inhibitors, including depression, panic and OCD, and is not beneficial in schizophrenia, Alzheimer’s ADDH, autism or ECT-induced cognitive impairment.

DMAE – “Smart” Micro-Nutrient

DMAE is a short for dimethylaminoethanol, a naturally occurring substance that facilitates the synthesis of a neurotransmitter acetylcholine. DMAE also may stimulate the synthesis of phosphatidylcholine, an important component of cell membranes. Interestingly, DMAE is far better known and researched as a "smart drug” although it is a natural compound. In a number of studies, DMAE has been shown to reduce age- related decline in cognitive ability and memory. It was also found to modestly increase life span of laboratory animals. An intriguing finding in some DMAE studies was that it reduced the accumulation of lipofuscin deposits inside cells.

Lipofuscin is a cellular pigment consisting of aggregated chunks of molecular waste. It tends to occur in the cells of older people. It is likely that lipofuscin is not simply a

byproduct of aging but also contributes to the aging process. Neurons, heart and skin of older people usually contain particularly large amounts of lipofiscin.

Green Tea 98% (45% ECGc) – Excellent Brain Nutrient on Multiple Levels

Green Tea is one of the most if not the most studied micro-nutrients in history but few people associate Green Tea Extract with brain health; however, it has incredible benefits and a brain supplement that did not incorporate it would be incomplete.

Take polyphenols, for instance. These phyto-chemicals, which give green tea its bitter taste, are powerful antioxidants that have been associated with preventing cancer and heart attacks. Recent research has also shown they may help maintain positive mood states and protect against Parkinson's disease and other brain disorders.

A study from the University of San Francisco found that the polyphenols in green tea can boost availability of the important brain substance dopamine in the areas where it's needed. Dopamine is a signaling substance in brain circuits that are crucial to creating positive mood states.

It is involved in transmitting signals of reward and motivation and in helping muscles move smoothly. Dopamine production goes awry in the brains of Parkinson's patients, leading to the muscle rigidity and tremors associated with the disorder.

Researchers in the study measured levels of dopamine in mice before treating some of them with polyphenols. They then injured the specific neurons linked to Parkinson's disease in all of the mice and measured dopamine levels again. The mice treated with polyphenols appeared to have been protected against toxic elements that may be linked to this disease.

Other studies in animals show that the polyphenols in green tea also help the brain and body maintain a steady supply of their chief fuel, glucose. Polyphenols influence glucose metabolism in part by helping the body regulate sensitivity to the hormone insulin. Compounds in green tea enhance insulin sensitivity, keeping the brain running smoothly on steady levels of glucose.

Tannins are another important set of compounds found in green tea. They too have also been shown to have brain boosting benefits: they may prevent the brain damage that occurs after strokes and other brain injuries.

Tannins, like many other beneficial substances in plants, are natural compounds produced by tea leaves in the wild to keep animals from devouring the growing plants. It now turns out that one of the tannins found in tea leaves, gallotannin, helps the body's

own DNA repair system and keeps it working in the brain despite damage that occurs during stroke.

Under normal conditions, the DNA repair system in the brain goes into overdrive in the aftermath of stroke, and instead of helping to repair brain cells it causes them to die. But researchers at the University of California at San Francisco found that if they surround injured neurons with the gallotannin found in green tea, it is highly effective in preventing neuron death.

This doesn't necessarily mean that consuming large amounts of green tea would be sufficient to repair brain damage in stroke victims. The amount of gallotannins found in green tea is negligible compared to the large amount used in the study.

Acetyl-L-Carnitine (Key ingredient of OxyAGE)

Acetyl-l-carnitine (also spelled as acetyl l-carnitine, or l-acetyl-l-carnitine) and carnitine play several important roles in the human body. These nutrients shuttle acetyl groups and fatty acids into mitochondria for energy production.

Without carnitine, fatty acids cannot easily enter into mitochondria. The acetyl group of acetyl l carnitine is used to form acetyl-CoA, the most important intermediary in the generation of energy from amino acids, fats, and carbohydrates. Therefore, acetyl l carnitine serves as an energy reservoir of acetyl groups and both acetyl-l-carnitine and carnitine help improve energy production. The acetyl group is also used to make the important brain chemical acetylcholine. Some studies suggest that perhaps acetyl l carnitine can even act as a neurotransmitter itself. This name of this nutrient is sometimes abbreviated as ALC or ALCAR.

Those who take carnitine pills, usually for energy or weight loss, notice an increase in physical energy, but not as much mental energy. Acetyl-l-carnitine has a significantly more immediate and noticeable mental effect than carnitine because it crosses into the brain much better. The mind boosting effect of ALC is often noticed within a few hours, or even within an hour. Most people report feeling mentally sharper, having more focus and being more alert. Some find a mild mood enhancement.

Phosphatidyl Serine

A phospholipid nutrient that is made of glycerophosphate skeleton through linking of fatty acids and L-serine

Phosphatidyl Serine allows brain cells to metabolize glucose, discharges and binds with neurotransmitters and enhances learning, memory and other cognitive functions.


Phosphatidyl Choline

Phosphatidyl choline (PC) is a fat-soluble substance known as a phospholipid. Phospholipids are essential components of cell membranes. Phosphatidylcholine's role in the maintenance of cell membrane integrity is vital to all of the basic biological processes: information flow, intracellular communication, and bioenergetics. The commercial term for PC is lecithin. When people refer to lecithin they are usually referring to supplements high in phosphatidyl choline. Supplements labeled as lecithin may contain from 10 to 20 PC. However, pure PC supplements are generally labeled as phosphatidylcholine.

In addition to providing choline needed for cell membrane integrity, PC is also an essential component of acetylcholine, a neurotransmitter required for normal brain activity. Although the human body can synthesize choline, additional amounts from the diet are considered essential under certain circumstances. Consequently, PC has been employed by researchers in a number of studies for use in connection with various neurological and psychiatric disorders. However, these studies did not draw any conclusive results regarding PC supplementation.

Huperzine A

Huperzine A is a potent chemical derived from a particular type of club moss ( Huperzia serrata [Thumb] Trev.). Like caffeine and cocaine, huperzine A is a medicinally active, plant-derived chemical that belongs to the class known as alkaloids. It was first isolated in 1948 by Chinese scientists.

Studies in animals suggested that it could improve memory skills. These finding led to human trials and the subsequent marketing of the huperzine A as a treatment for Alzheimer’s disease and related conditions. It is also used as a “brain booster” for enhancing memory and mental function.

Huperzine A inhibits the enzyme acetylcholinesterase (uh-SEE-tul-co-lin-ES-ter-ase). This enzyme breaks down acetylcholine, a substance that plays an important role in mental function. When the enzyme that breaks it down is inhibited, acetylcholine levels in the brain tend to rise.

Drugs that inhibit acetylcholinesterase (such as tacrine and donepezil) improve memory and mental functioning in people with Alzheimer's and other severe conditions. The research on huperzine A indicates that it works in much the same way.

The chemical action of huperzine A is very precise and specific. It "fits" into a niche on the enzyme where acetylcholine is supposed to attach. Because huperzine A is in the way, the enzyme can't grab and destroy acetylcholine. This mechanism has been demonstrated by considerable scientific work, including sophisticated computer modeling of the shape of the molecule. Huperzine may also help protect nerve cells from damage.

Disclaimer

Natural Biology makes no claims that Brain Rocket can be used to treat, cure, or prevent any disease. These statements have not been evaluated by the FDA and are based entirely upon meta-analysis of major university research. If you have any condition which you feel may be impaired by any substance, always consult your physician prior to use, including Brain Rocket.